Definition
What TGF-β1 measures
Transforming growth factor beta-1 is a cytokine involved in immune regulation and tissue remodeling. Shoemaker protocols treat it as a core CIRS marker.
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Innate immunityCompletepg/mL
TGF-β1
A core Shoemaker remodeling and immune-regulation marker
Illustrative sample band · Synthetic
1,800pg/mL
0Sample target 0–2,380 pg/mL2,570
Why it matters
How clinicians usually read it
It requires platelet-poor EDTA plasma, multi-spin within minutes, and a frozen send-out. A mailed Tasso+ tube will falsely elevate it. Complete is a venous clinic draw for this reason.
When it reads low
A lower value can mean
A lower TGF-β1 is closer to the quiet published band used in CIRS workups. It is still read as part of a pattern, not a single-marker all-clear.
When it reads high
A higher value can mean
A higher TGF-β1 is a hallmark CIRS pattern when the specimen was handled correctly. Values far above the usual assay ceiling often mean platelets were left in the sample.
Questions for a clinician
Bring the number into a real conversation
01
Was this drawn as platelet-poor plasma and frozen the way the lab requires?
02
How does this sit with C4a, MMP-9, and MSH?
03
Is this a number you treat, or a mishandled tube we should repeat?
Educational boundary
Educational information only. Displayed ranges are illustrative sample bands, not a diagnosis, treatment plan, or substitute for the contracted laboratory report and a qualified clinician.
See it as a sample result
The sample dashboard shows an illustrative reading, target band, and trend for TGF-β1.